RAB5A

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
RAB5A	RAB5	RAB5A, member RAS oncogene family	NM_004162	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

RAB5A is a member of the RAS oncogene family. It is required for the fusion of plasma membranes and early endosomes and contributes to the regulation of filopodia extension.

It is constantly expressed in both human cells and bat cells, but an upregulation in human cells 23 h after Ebola infection can be observed. %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

\igvfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00409/snapshots//hg19.goi.00409_igv.eps % \caption\igv of gene RAB5A. % <- say something about the figure here \endfigure }

\sashimifigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00409/snapshots//hg19.goi.00409_sashimi.eps % \caption\sashimi of gene RAB5A. % <- say something about the figure here \endfigure }

\ucscfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00409/snapshots//hg19.goi.00409_ucsc.eps % \caption\ucsc of gene RAB5A. % <- say something about the figure here \endfigure }

\setcounterfigure0 \enddocument

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	222	203	215	268	285	530	319	268	302
Read_Max	R. aegyptiacus	Transcriptome	196	170	126	170	159	180	199	183	168
Read_Max	R. aegyptiacus	Genome	276	232	127	197	166	149	203	313	285
DESeq	H. sapiens	Genome	3078.85	2246.76	2900.05	2784.27	2708.13	5492.34	2780.86	2140.06	3392.43
DESeq	R. aegyptiacus	Transcriptome	958.76	860.58	705.83	927.66	950.44	1018.56	1017.74	890.83	776.87
DESeq	R. aegyptiacus	Genome	2463.87	2390.32	1924.72	2343.3	2425.36	3008.97	3057.6	2355.84	2292.03

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3078.85	2784.27	2780.86	-0.15	-0.15	-0.0
7h	2246.76	2708.13	2140.06	0.27	-0.07	-0.34
23h	2900.05	5492.34	3392.43	0.92	0.23	-0.7

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3078.85	2246.76	2900.05	-0.45	-0.09	0.37
Ebov	2784.27	2708.13	5492.34	-0.04	0.98	1.02
Marv	2780.86	2140.06	3392.43	-0.38	0.29	0.66

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	958.76	927.66	1017.74	-0.05	0.09	0.13
7h	860.58	950.44	890.83	0.14	0.05	-0.09
23h	705.83	1018.56	776.87	0.53	0.14	-0.39

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	958.76	860.58	705.83	-0.16	-0.44	-0.29
Ebov	927.66	950.44	1018.56	0.03	0.13	0.1
Marv	1017.74	890.83	776.87	-0.19	-0.39	-0.2

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material