FOXP1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FOXP1 12CC4, hFKH1B, HSPC215, QRF1,QRF1, 12CC4 forkhead box P1 NM_032682 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.

It is constantly expressed in both species but at a distinct higher level in bat cells. %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

\igvfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv2.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv3.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv4.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv5.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv6.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv7.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv8.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_igv9.eps % \caption\igv of gene FOXP1. % <- say something about the figure here \endfigure }

\sashimifigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi2.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi3.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi4.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi5.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi6.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi7.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi8.eps \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_sashimi9.eps % \caption\sashimi of gene FOXP1. % <- say something about the figure here \endfigure }

\ucscfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00451/snapshots//hg19.goi.00451_ucsc.eps % \caption\ucsc of gene FOXP1. % <- say something about the figure here \endfigure }

\setcounterfigure0 \enddocument

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome165 102 83 102 118 110 143 121 72
Read_Max
batR. aegyptiacusTranscriptome 243 206 113 178 152 210 220 217 214
Read_Max
bat_genomeR. aegyptiacusGenome 266 182 90 203 123 123 184 233 234
DESeq
humanH. sapiensGenome 3312.25 2227.38 2083.95 2396.43 2339.05 2132.79 2272.96 1905.85 2239.85
DESeq
batR. aegyptiacusTranscriptome 2256.78 1911.69 1421.65 1631.81 1524.27 1839.8 2438.28 1492.31 1384.79
DESeq
bat_genomeR. aegyptiacusGenome 3517.48 2596.59 3207.86 2968.38 2481.17 2691.76 3549.02 2399.45 2339.97

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3312.25 2396.43 2272.96 -0.47 -0.54 -0.08
7h 2227.38 2339.05 1905.85 0.07 -0.22 -0.3
23h 2083.95 2132.79 2239.85 0.03 0.1 0.07

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3312.25 2227.38 2083.95 -0.57 -0.67 -0.1
Ebov 2396.43 2339.05 2132.79 -0.03 -0.17 -0.13
Marv 2272.96 1905.85 2239.85 -0.25 -0.02 0.23

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2256.78 1631.81 2438.28 -0.47 0.11 0.58
7h 1911.69 1524.27 1492.31 -0.33 -0.36 -0.03
23h 1421.65 1839.8 1384.79 0.37 -0.04 -0.41

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2256.78 1911.69 1421.65 -0.24 -0.67 -0.43
Ebov 1631.81 1524.27 1839.8 -0.1 0.17 0.27
Marv 2438.28 1492.31 1384.79 -0.71 -0.82 -0.11