DICER1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
DICER1 HERNA, MNG1, KIAA0928, RMSE2,Dicer, K12H4.8-LIKE, HERNA dicer 1, ribonuclease type III pdf

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Description

Homo sapiens dicer 1, ribonuclease type III (DICER1), transcript variant 3, mRNA. This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome155 117 99 88 142 65 106 92 64
Read_Max
batR. aegyptiacusTranscriptome 154 120 88 115 107 127 93 145 112
Read_Max
bat_genomeR. aegyptiacusGenome 147 121 70 83 96 59 95 175 127
DESeq
humanH. sapiensGenome 4173.8 3658.26 3582.12 3283.89 4158.43 1859.08 2929.99 2797.93 2994.47
DESeq
batR. aegyptiacusTranscriptome 3028.03 2542.53 2561.34 2899.09 2873.42 2875.33 2833.19 2711.79 2459.81
DESeq
bat_genomeR. aegyptiacusGenome 1442.92 1298.75 1264.18 1208.68 1555.89 1387.65 1333.7 1468.54 1146.44

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4173.8 3283.89 2929.99 -0.35 -0.51 -0.16
7h 3658.26 4158.43 2797.93 0.18 -0.39 -0.57
23h 3582.12 1859.08 2994.47 -0.95 -0.26 0.69

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4173.8 3658.26 3582.12 -0.19 -0.22 -0.03
Ebov 3283.89 4158.43 1859.08 0.34 -0.82 -1.16
Marv 2929.99 2797.93 2994.47 -0.07 0.03 0.1

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3028.03 2899.09 2833.19 -0.06 -0.1 -0.03
7h 2542.53 2873.42 2711.79 0.18 0.09 -0.08
23h 2561.34 2875.33 2459.81 0.17 -0.06 -0.23

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3028.03 2542.53 2561.34 -0.25 -0.24 0.01
Ebov 2899.09 2873.42 2875.33 -0.01 -0.01 0.0
Marv 2833.19 2711.79 2459.81 -0.06 -0.2 -0.14