CHUK

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CHUK IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 ,IKK1, IkBKA conserved helix-loop-helix ubiquitous kinase NM_001278 pdf

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Description

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

It is constantly expressed in human cells and bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome217 258 215 228 293 218 261 286 185
Read_Max
batR. aegyptiacusTranscriptome 253 172 164 235 188 212 237 263 220
Read_Max
bat_genomeR. aegyptiacusGenome 296 249 140 170 164 130 211 337 257
DESeq
humanH. sapiensGenome 3260.5 3312.53 3330.93 3286.17 3669.85 3080.26 3276.48 3331.89 3022.74
DESeq
batR. aegyptiacusTranscriptome 2070.27 1885.36 1733.14 2048.43 2052.1 1898.83 2438.28 2168.97 1782.78
DESeq
bat_genomeR. aegyptiacusGenome 3214.98 3172.49 2751.51 2912.09 3045.93 2820.99 3600.75 3315.31 2693.58

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3260.5 3286.17 3276.48 0.01 0.01 -0.0
7h 3312.53 3669.85 3331.89 0.15 0.01 -0.14
23h 3330.93 3080.26 3022.74 -0.11 -0.14 -0.03

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3260.5 3312.53 3330.93 0.02 0.03 0.01
Ebov 3286.17 3669.85 3080.26 0.16 -0.09 -0.25
Marv 3276.48 3331.89 3022.74 0.02 -0.12 -0.14

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2070.27 2048.43 2438.28 -0.02 0.24 0.25
7h 1885.36 2052.1 2168.97 0.12 0.2 0.08
23h 1733.14 1898.83 1782.78 0.13 0.04 -0.09

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2070.27 1885.36 1733.14 -0.13 -0.26 -0.12
Ebov 2048.43 2052.1 1898.83 0.0 -0.11 -0.11
Marv 2438.28 2168.97 1782.78 -0.17 -0.45 -0.28