KIF13A

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
KIF13A bA500C11.2 kinesin family member 13A pdf NONE

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Description

This gene seems to be moderately equally expressed in the different conditions and time points. This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome75 126 88 96 123 106 99 110 91
Read_Max
batR. aegyptiacusTranscriptome 326 234 177 236 194 261 218 260 234
Read_Max
bat_genomeR. aegyptiacusGenome 360 248 147 225 162 142 186 310 258
DESeq
humanH. sapiensGenome 2218.31 2211.06 2223.93 2169.44 2086.22 2088.05 1994.89 2148.85 2587.8
DESeq
batR. aegyptiacusTranscriptome 6513.77 5777.54 4998.31 5235.88 5508.21 6031.95 6581.99 5215.2 5204.64
DESeq
bat_genomeR. aegyptiacusGenome 6464.33 5254.33 4733.13 5979.21 5491.38 5967.03 6472.81 4995.56 5028.41

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2218.31 2169.44 1994.89 -0.03 -0.15 -0.12
7h 2211.06 2086.22 2148.85 -0.08 -0.04 0.04
23h 2223.93 2088.05 2587.8 -0.09 0.22 0.31

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2218.31 2211.06 2223.93 -0.0 0.0 0.01
Ebov 2169.44 2086.22 2088.05 -0.06 -0.06 0.0
Marv 1994.89 2148.85 2587.8 0.11 0.38 0.27

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 6513.77 5235.88 6581.99 -0.32 0.02 0.33
7h 5777.54 5508.21 5215.2 -0.07 -0.15 -0.08
23h 4998.31 6031.95 5204.64 0.27 0.06 -0.21

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 6513.77 5777.54 4998.31 -0.17 -0.38 -0.21
Ebov 5235.88 5508.21 6031.95 0.07 0.2 0.13
Marv 6581.99 5215.2 5204.64 -0.34 -0.34 -0.0