NF1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
NF1 NFNS, VRNF, WSS neurofibromin 1 NM_000267 pdf

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Description

Homo sapiens neurofibromin 1 (NF1), transcript variant 3, mRNA. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome649 654 557 489 749 263 591 804 534
Read_Max
batR. aegyptiacusTranscriptome 212 185 121 177 149 256 150 163 198
Read_Max
bat_genomeR. aegyptiacusGenome 216 177 102 173 131 144 126 182 218
DESeq
humanH. sapiensGenome 7323.7 7144.19 8046.85 6804.03 7813.46 11452.16 5932.66 5999.33 7338.42
DESeq
batR. aegyptiacusTranscriptome 7755.5 6156.95 5993.86 7557.09 7823.23 12142.46 7256.11 6423.12 6828.1
DESeq
bat_genomeR. aegyptiacusGenome 8748.59 8022.5 6315.3 7293.55 8574.14 13991.38 8417.12 6910.52 7567.88

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7323.7 6804.03 5932.66 -0.11 -0.3 -0.2
7h 7144.19 7813.46 5999.33 0.13 -0.25 -0.38
23h 8046.85 11452.16 7338.42 0.51 -0.13 -0.64

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7323.7 7144.19 8046.85 -0.04 0.14 0.17
Ebov 6804.03 7813.46 11452.16 0.2 0.75 0.55
Marv 5932.66 5999.33 7338.42 0.02 0.31 0.29

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7755.5 7557.09 7256.11 -0.04 -0.1 -0.06
7h 6156.95 7823.23 6423.12 0.35 0.06 -0.28
23h 5993.86 12142.46 6828.1 1.02 0.19 -0.83

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7755.5 6156.95 5993.86 -0.33 -0.37 -0.04
Ebov 7557.09 7823.23 12142.46 0.05 0.68 0.63
Marv 7256.11 6423.12 6828.1 -0.18 -0.09 0.09