NF1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
NF1	NFNS, VRNF, WSS	neurofibromin 1	NM_000267	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens neurofibromin 1 (NF1), transcript variant 3, mRNA. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	649	654	557	489	749	263	591	804	534
Read_Max	R. aegyptiacus	Transcriptome	212	185	121	177	149	256	150	163	198
Read_Max	R. aegyptiacus	Genome	216	177	102	173	131	144	126	182	218
DESeq	H. sapiens	Genome	7323.7	7144.19	8046.85	6804.03	7813.46	11452.16	5932.66	5999.33	7338.42
DESeq	R. aegyptiacus	Transcriptome	7755.5	6156.95	5993.86	7557.09	7823.23	12142.46	7256.11	6423.12	6828.1
DESeq	R. aegyptiacus	Genome	8748.59	8022.5	6315.3	7293.55	8574.14	13991.38	8417.12	6910.52	7567.88

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	7323.7	6804.03	5932.66	-0.11	-0.3	-0.2
7h	7144.19	7813.46	5999.33	0.13	-0.25	-0.38
23h	8046.85	11452.16	7338.42	0.51	-0.13	-0.64

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	7323.7	7144.19	8046.85	-0.04	0.14	0.17
Ebov	6804.03	7813.46	11452.16	0.2	0.75	0.55
Marv	5932.66	5999.33	7338.42	0.02	0.31	0.29

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	7755.5	7557.09	7256.11	-0.04	-0.1	-0.06
7h	6156.95	7823.23	6423.12	0.35	0.06	-0.28
23h	5993.86	12142.46	6828.1	1.02	0.19	-0.83

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	7755.5	6156.95	5993.86	-0.33	-0.37	-0.04
Ebov	7557.09	7823.23	12142.46	0.05	0.68	0.63
Marv	7256.11	6423.12	6828.1	-0.18	-0.09	0.09

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material

NF1