TNFRSF4
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| TNFRSF4 | OX40, ACT35,ACT35, OX40, CD134 | tumor necrosis factor receptor superfamily, member 4 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the TNF-receptorsuperfamily. This receptor has been shown to activate NF-kappaB through itsinteraction with adaptor proteins TRAF2 and TRAF5. Knockout studies in micesuggested that this receptor promotes the expression of apoptosis inhibitorsBCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockoutstudies also suggested the roles of this receptor in CD4+ T cell response,as well as in T cell-dependent B cell proliferation and differentiation.
This gene was found to be no expressed in all probes.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 2 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | 2 | 0 | 2 | 0 | 2 | 0 | 0 | 3 | 0 |
DESeq | | H. sapiens | Genome | 1.0 | 1.0 | 1.0 | 1.0 | 2.63 | 1.0 | 1.0 | 2.6 | 3.17 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | 1.72 | 0.0 | 4.46 | 0.0 | 2.23 | 0.0 | 0.0 | 1.59 | 0.0 |