ITGA9

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ITGA9 ALPHA-RLC, ITGA4L, RLC,RLC, ALPHA-RLC integrin, alpha 9 NM_002207 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The integrin, alpha 9 is involved in the PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules (CAMs), Regulation of actin cytoskeleton, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy.

It seems not to be expressed in bat cells in the samples analyzed. It seems to be downregulated after 23 h of Ebola infection in human cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome6 7 10 6 6 15 6 9 9
Read_Max
batR. aegyptiacusTranscriptome 2 NA 2 1 NA 2 NA NA 2
Read_Max
bat_genomeR. aegyptiacusGenome 5 4 3 2 2 2 1 3 2
DESeq
humanH. sapiensGenome 97.4 81.57 106.24 64.88 85.55 47.06 76.44 88.13 102.12
DESeq
batR. aegyptiacusTranscriptome 2.68 1.0 3.44 1.92 1.0 3.57 1.0 1.0 2.75
DESeq
bat_genomeR. aegyptiacusGenome 12.89 27.38 12.27 12.84 7.81 23.5 6.75 11.1 13.7

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 97.4 64.88 76.44 -0.59 -0.35 0.24
7h 81.57 85.55 88.13 0.07 0.11 0.04
23h 106.24 47.06 102.12 -1.17 -0.06 1.12

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 97.4 81.57 106.24 -0.26 0.13 0.38
Ebov 64.88 85.55 47.06 0.4 -0.46 -0.86
Marv 76.44 88.13 102.12 0.21 0.42 0.21

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2.68 1.92 1.0 -0.48 -1.42 -0.94
7h 1.0 1.0 1.0 0.0 0.0 0.0
23h 3.44 3.57 2.75 0.05 -0.32 -0.38

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2.68 1.0 3.44 -1.42 0.36 1.78
Ebov 1.92 1.0 3.57 -0.94 0.89 1.84
Marv 1.0 1.0 2.75 0.0 1.46 1.46