MKNK1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MKNK1 | MNK1 | MAP kinase interacting serine/threonine kinase 1 | NM_003684 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a Ser/Thr protein kinase that interacts with, and isactivated by ERK1 and p38 mitogen-activated protein kinases, and thus mayplay a role in the response to environmental stress and cytokines. Thiskinase may also regulate transcription by phosphorylating eIF4E viainteraction with the C-terminal region of eIF4G. Alternatively splicedtranscript variants have been noted for this gene.
It is constantly expressed in human cells and bat cells at low level.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 36 | 55 | 43 | 46 | 68 | 70 | 57 | 75 | 76 |
Read_Max |  | R. aegyptiacus | Transcriptome | 49 | 42 | 62 | 46 | 36 | 60 | 47 | 62 | 72 |
Read_Max |  | R. aegyptiacus | Genome | 70 | 75 | 64 | 78 | 48 | 51 | 52 | 112 | 96 |
DESeq | | H. sapiens | Genome | 357.19 | 566.01 | 542.09 | 452.71 | 527.79 | 597.11 | 509.78 | 598.11 | 560.98 |
DESeq | | R. aegyptiacus | Transcriptome | 204.31 | 208.86 | 247.75 | 213.44 | 210.16 | 283.3 | 245.73 | 258.78 | 247.67 |
DESeq | | R. aegyptiacus | Genome | 645.4 | 843.32 | 753.15 | 682.35 | 841.56 | 758.44 | 752.31 | 849.25 | 701.22 |