CD86

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CD86 CD86, B7-2, B7.2, B70, CD28LG2, LAB72,B7.2 CD86 molecule NM_006889 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell.

CD86 did not show a response due to Marburg or Ebola virus infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome7 6 6 4 9 5 6 8 13
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 0 2 0 0 0 1 0 0 0
DESeq
humanH. sapiensGenome 6.07 1.0 5.96 10.13 4.25 3.63 5.39 8.19 17.31
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 0.0 1.83 0.0 0.0 0.0 2.61 0.0 0.0 0.0

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 6.07 10.13 5.39 0.74 -0.17 -0.91
7h 1.0 4.25 8.19 2.09 3.03 0.95
23h 5.96 3.63 17.31 -0.72 1.54 2.25

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 6.07 1.0 5.96 -2.6 -0.03 2.58
Ebov 10.13 4.25 3.63 -1.25 -1.48 -0.23
Marv 5.39 8.19 17.31 0.6 1.68 1.08

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA