FLNA

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
FLNA	FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD,ABP-280	filamin A, alpha		pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins.

Highly but not differentially expressed in human cells. Its bat cells homolog seems to be induced due to Marburg vius infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	519	642	368	529	648	1399	774	1023	825
Read_Max	R. aegyptiacus	Transcriptome	3522	2689	2328	2737	2772	3016	2489	3246	4153
Read_Max	R. aegyptiacus	Genome	3648	2710	1912	2481	2226	1727	2055	3782	4481
DESeq	H. sapiens	Genome	22245.13	21497.88	11832.49	21581.58	17977.78	47640.02	25589.94	28598.56	32581.17
DESeq	R. aegyptiacus	Transcriptome	74050.14	65548.91	57983.68	62050.35	67140.97	62671.59	71118.23	57977.7	70701.96
DESeq	R. aegyptiacus	Genome	109643.56	85486.63	79712.28	102499.81	97734.26	98653.75	113904.98	78542.89	104285.0

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	22245.13	21581.58	25589.94	-0.04	0.2	0.25
7h	21497.88	17977.78	28598.56	-0.26	0.41	0.67
23h	11832.49	47640.02	32581.17	2.01	1.46	-0.55

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	22245.13	21497.88	11832.49	-0.05	-0.91	-0.86
Ebov	21581.58	17977.78	47640.02	-0.26	1.14	1.41
Marv	25589.94	28598.56	32581.17	0.16	0.35	0.19

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	74050.14	62050.35	71118.23	-0.26	-0.06	0.2
7h	65548.91	67140.97	57977.7	0.03	-0.18	-0.21
23h	57983.68	62671.59	70701.96	0.11	0.29	0.17

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	74050.14	65548.91	57983.68	-0.18	-0.35	-0.18
Ebov	62050.35	67140.97	62671.59	0.11	0.01	-0.1
Marv	71118.23	57977.7	70701.96	-0.29	-0.01	0.29

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material