FGFR2

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
FGFR2	FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25,CEK3	fibroblast growth factor receptor 2	NM_022976, NM_000141	pdf		NONE	NONE	NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development.

FGFR2 shows no expression in the analysed samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	1	1	0	2	1	0	2	1	1
Read_Max	R. aegyptiacus	Transcriptome	109	82	43	62	57	40	66	78	43
Read_Max	R. aegyptiacus	Genome	130	72	39	85	51	25	64	95	53
DESeq	H. sapiens	Genome	1.0	1.0	1.0	3.28	1.0	1.0	2.75	1.8	1.0
DESeq	R. aegyptiacus	Transcriptome	1083.94	1054.83	561.69	709.73	785.08	433.43	1062.24	756.98	434.86
DESeq	R. aegyptiacus	Genome	1908.71	1344.38	1096.81	1880.17	1498.97	835.46	1990.42	1409.07	834.79

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1.0	3.28	2.75	1.71	1.46	-0.25
7h	1.0	1.0	1.8	0.0	0.85	0.85
23h	1.0	1.0	1.0	0.0	0.0	0.0

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1.0	1.0	1.0	0.0	0.0	0.0
Ebov	3.28	1.0	1.0	-1.71	-1.71	0.0
Marv	2.75	1.8	1.0	-0.61	-1.46	-0.85

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1083.94	709.73	1062.24	-0.61	-0.03	0.58
7h	1054.83	785.08	756.98	-0.43	-0.48	-0.05
23h	561.69	433.43	434.86	-0.37	-0.37	0.0

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1083.94	1054.83	561.69	-0.04	-0.95	-0.91
Ebov	709.73	785.08	433.43	0.15	-0.71	-0.86
Marv	1062.24	756.98	434.86	-0.49	-1.29	-0.8

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material