IL11

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
IL11 IL11, AGIF, IL-11,IL-11 interleukin 11 NM_000641 pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Not expressed in the examned samples.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome0 2 0 2 1 2 0 2 2
Read_Max
batR. aegyptiacusTranscriptome 26 19 18 26 29 60 14 37 43
Read_Max
bat_genomeR. aegyptiacusGenome 30 18 19 19 23 38 13 34 49
DESeq
humanH. sapiensGenome 1.0 3.04 1.0 3.28 1.81 7.58 1.0 2.6 3.17
DESeq
batR. aegyptiacusTranscriptome 81.65 69.08 91.39 88.9 121.46 267.9 56.62 103.45 152.32
DESeq
bat_genomeR. aegyptiacusGenome 143.52 134.16 188.57 123.44 167.42 488.22 85.46 143.52 237.17

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 3.28 1.0 1.71 0.0 -1.71
7h 3.04 1.81 2.6 -0.75 -0.23 0.52
23h 1.0 7.58 3.17 2.92 1.66 -1.26

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 3.04 1.0 1.6 0.0 -1.6
Ebov 3.28 1.81 7.58 -0.86 1.21 2.07
Marv 1.0 2.6 3.17 1.38 1.66 0.29

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 81.65 88.9 56.62 0.12 -0.53 -0.65
7h 69.08 121.46 103.45 0.81 0.58 -0.23
23h 91.39 267.9 152.32 1.55 0.74 -0.81

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 81.65 69.08 91.39 -0.24 0.16 0.4
Ebov 88.9 121.46 267.9 0.45 1.59 1.14
Marv 56.62 103.45 152.32 0.87 1.43 0.56