WASL
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| WASL | N-WASP, NWASP | Wiskott-Aldrich syndrome-like | NM_003941 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.
It is upregulated in human cells after 23 h of Ebola infection and transcribed constantly in bat cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 355 | 352 | 341 | 329 | 427 | 728 | 481 | 330 | 312 |
Read_Max |  | R. aegyptiacus | Transcriptome | 309 | 259 | 242 | 292 | 234 | 359 | 268 | 358 | 268 |
Read_Max |  | R. aegyptiacus | Genome | 340 | 294 | 195 | 251 | 196 | 198 | 227 | 425 | 297 |
DESeq | | H. sapiens | Genome | 5334.72 | 4231.43 | 4915.48 | 5083.88 | 4835.62 | 9213.77 | 4899.31 | 3655.63 | 5040.85 |
DESeq | | R. aegyptiacus | Transcriptome | 2252.58 | 2028.78 | 2447.74 | 2241.64 | 2255.79 | 2885.59 | 2371.54 | 2213.59 | 2027.7 |
DESeq | | R. aegyptiacus | Genome | 3480.53 | 3613.32 | 3526.97 | 3203.4 | 3715.61 | 4694.25 | 3862.77 | 3636.45 | 3256.1 |