ITGB8

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ITGB8 integrin, beta 8 NM_002214 pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

The expression level of this gene in human samples is very low, no homolog was found in bats

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome5 4 17 5 6 15 8 6 3
Read_Max
batR. aegyptiacusTranscriptome 119 73 70 87 61 48 56 78 58
Read_Max
bat_genomeR. aegyptiacusGenome 108 89 58 63 53 23 72 116 68
DESeq
humanH. sapiensGenome 74.06 56.07 70.5 72.86 69.29 185.23 56.26 58.55 58.63
DESeq
batR. aegyptiacusTranscriptome 878.11 683.58 716.82 675.85 652.58 270.47 691.8 585.13 462.85
DESeq
bat_genomeR. aegyptiacusGenome 2752.63 2339.21 2150.1 2337.37 2276.91 907.26 2563.93 2135.4 1503.47

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 74.06 72.86 56.26 -0.02 -0.4 -0.37
7h 56.07 69.29 58.55 0.31 0.06 -0.24
23h 70.5 185.23 58.63 1.39 -0.27 -1.66

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 74.06 56.07 70.5 -0.4 -0.07 0.33
Ebov 72.86 69.29 185.23 -0.07 1.35 1.42
Marv 56.26 58.55 58.63 0.06 0.06 0.0

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 878.11 675.85 691.8 -0.38 -0.34 0.03
7h 683.58 652.58 585.13 -0.07 -0.22 -0.16
23h 716.82 270.47 462.85 -1.41 -0.63 0.78

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 878.11 683.58 716.82 -0.36 -0.29 0.07
Ebov 675.85 652.58 270.47 -0.05 -1.32 -1.27
Marv 691.8 585.13 462.85 -0.24 -0.58 -0.34