TNFRSF9

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TNFRSF9 4-1BB, CD137, ILA,CD137, 4-1BB tumor necrosis factor receptor superfamily, member 9 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the TNF-receptorsuperfamily. This receptor contributes to the clonal expansion, survival,and development of T cells. It can also induce proliferation in peripheralmonocytes, enhance T cell apoptosis induced by TCR/CD3 triggeredactivation, and regulate CD28 co-stimulation to promote Th1 cellresponses.

The expression of this receptor seems not to be effected by Marburg or Ebolavirus infection.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4 2 0 6 1 6 5 1 5
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 0 1 0 1 0 1 0 3 1
DESeq
humanH. sapiensGenome 23.33 6.1 1.0 19.25 2.63 27.32 14.16 1.8 8.61
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.91 0.0 1.97 0.0 2.61 0.0 1.59 0.86

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 23.33 19.25 14.16 -0.28 -0.72 -0.44
7h 6.1 2.63 1.8 -1.21 -1.76 -0.55
23h 1.0 27.32 8.61 4.77 3.11 -1.67

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 23.33 6.1 1.0 -1.94 -4.54 -2.61
Ebov 19.25 2.63 27.32 -2.87 0.51 3.38
Marv 14.16 1.8 8.61 -2.98 -0.72 2.26

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA