ERBB2

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
ERBB2	CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1,NEU, CD340	erb-b2 receptor tyrosine kinase 2	NM_004448	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) is involved in the ErbB, Calcium and HIF-1 signaling pathway, Focal adhesion, Adherens junction, Pathways in cancer and Central carbon metabolism in cancer.

It does not present any particular differential expression pattern in the analyzed samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	62	78	55	58	59	145	84	54	67
Read_Max	R. aegyptiacus	Transcriptome	55	68	46	58	54	34	48	87	63
Read_Max	R. aegyptiacus	Genome	70	60	40	64	49	26	40	111	63
DESeq	H. sapiens	Genome	1261.37	1215.67	1049.42	1240.92	934.27	2340.71	1403.65	1044.15	1341.7
DESeq	R. aegyptiacus	Transcriptome	946.16	969.51	937.92	1037.54	1103.76	640.02	892.04	1152.73	871.34
DESeq	R. aegyptiacus	Genome	1312.29	1382.72	1293.19	1450.61	1554.77	930.76	1304.46	1485.19	1120.75

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1261.37	1240.92	1403.65	-0.02	0.15	0.18
7h	1215.67	934.27	1044.15	-0.38	-0.22	0.16
23h	1049.42	2340.71	1341.7	1.16	0.35	-0.8

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1261.37	1215.67	1049.42	-0.05	-0.27	-0.21
Ebov	1240.92	934.27	2340.71	-0.41	0.92	1.33
Marv	1403.65	1044.15	1341.7	-0.43	-0.07	0.36

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	946.16	1037.54	892.04	0.13	-0.08	-0.22
7h	969.51	1103.76	1152.73	0.19	0.25	0.06
23h	937.92	640.02	871.34	-0.55	-0.11	0.45

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	946.16	969.51	937.92	0.04	-0.01	-0.05
Ebov	1037.54	1103.76	640.02	0.09	-0.7	-0.79
Marv	892.04	1152.73	871.34	0.37	-0.03	-0.4

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material