TNF
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| TNF | TNF, DIF, TNF-alpha, TNFA, TNFSF2,TNFSF2 | tumor necrosis factor |  |
NONE | NONE | NONE |
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Description
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Not expressed in the examined transcriptome samples.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 2 | 0 |
Read_Max |  | R. aegyptiacus | Transcriptome | 7 | 3 | 10 | 2 | 5 | 16 | 3 | 11 | 15 |
Read_Max |  | R. aegyptiacus | Genome | 8 | 4 | 9 | 4 | 4 | 8 | 3 | 9 | 16 |
DESeq | | H. sapiens | Genome | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 3.63 | 1.0 | 2.6 | 1.0 |
DESeq | | R. aegyptiacus | Transcriptome | 10.24 | 5.54 | 30.32 | 6.49 | 21.81 | 60.03 | 12.12 | 20.0 | 37.74 |
DESeq | | R. aegyptiacus | Genome | 18.91 | 17.34 | 68.06 | 10.86 | 34.6 | 116.18 | 26.99 | 28.55 | 68.5 |