FIGF

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FIGF VEGFD,VEGF-D c-fos induced growth factor (vascular endothelial growth factor D) NM_004469 pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus.

The gene FIGF is not expressed in human cells or bat cells datasets.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome5 6 7 7 11 11 6 11 22
Read_Max
batR. aegyptiacusTranscriptome 5 8 18 10 4 2 4 6 8
Read_Max
bat_genomeR. aegyptiacusGenome 6 9 7 5 5 2 4 8 11
DESeq
humanH. sapiensGenome 73.05 143.78 145.95 96.82 182.29 101.01 73.81 97.72 86.9
DESeq
batR. aegyptiacusTranscriptome 16.96 17.34 54.75 33.96 13.05 6.13 11.01 24.13 26.37
DESeq
bat_genomeR. aegyptiacusGenome 24.06 63.89 94.84 28.64 36.83 15.66 23.62 44.4 59.08

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 73.05 96.82 73.81 0.41 0.01 -0.39
7h 143.78 182.29 97.72 0.34 -0.56 -0.9
23h 145.95 101.01 86.9 -0.53 -0.75 -0.22

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 73.05 143.78 145.95 0.98 1.0 0.02
Ebov 96.82 182.29 101.01 0.91 0.06 -0.85
Marv 73.81 97.72 86.9 0.4 0.24 -0.17

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 16.96 33.96 11.01 1.0 -0.62 -1.63
7h 17.34 13.05 24.13 -0.41 0.48 0.89
23h 54.75 6.13 26.37 -3.16 -1.05 2.1

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 16.96 17.34 54.75 0.03 1.69 1.66
Ebov 33.96 13.05 6.13 -1.38 -2.47 -1.09
Marv 11.01 24.13 26.37 1.13 1.26 0.13