ITGA6

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ITGA6 ITGA6, CD49f, ITGA6B, VLA-6,CD49f integrin, alpha 6 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

In human cells ITGA6 is strongly reduced in late infection phase of Ebola virus, only moderately reduced in Marburg virus infected cells. In bat cells, no effect is seen. %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

\igvfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00814/snapshots//hg19.goi.00814_igv.eps % \caption\igv of gene ITGA6. % <- say something about the figure here \endfigure }

\sashimifigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00814/snapshots//hg19.goi.00814_sashimi.eps % \caption\sashimi of gene ITGA6. % <- say something about the figure here \endfigure }

\ucscfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00814/snapshots//hg19.goi.00814_ucsc.eps % \caption\ucsc of gene ITGA6. % <- say something about the figure here \endfigure }

\setcounterfigure0 \enddocument

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome457 435 487 412 577 184 546 571 299
Read_Max
batR. aegyptiacusTranscriptome 17 19 11 8 9 15 11 12 18
Read_Max
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA
DESeq
humanH. sapiensGenome 9051.88 8717.85 10118.88 9555.36 9001.18 3294.75 8852.87 8223.92 6849.11
DESeq
batR. aegyptiacusTranscriptome 97.62 93.58 68.18 68.76 95.18 90.82 88.88 81.97 140.95
DESeq
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 9051.88 9555.36 8852.87 0.08 -0.03 -0.11
7h 8717.85 9001.18 8223.92 0.05 -0.08 -0.13
23h 10118.88 3294.75 6849.11 -1.62 -0.56 1.06

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 9051.88 8717.85 10118.88 -0.05 0.16 0.22
Ebov 9555.36 9001.18 3294.75 -0.09 -1.54 -1.45
Marv 8852.87 8223.92 6849.11 -0.11 -0.37 -0.26

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 97.62 68.76 88.88 -0.51 -0.14 0.37
7h 93.58 95.18 81.97 0.02 -0.19 -0.22
23h 68.18 90.82 140.95 0.41 1.05 0.63

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 97.62 93.58 68.18 -0.06 -0.52 -0.46
Ebov 68.76 95.18 90.82 0.47 0.4 -0.07
Marv 88.88 81.97 140.95 -0.12 0.67 0.78