MYD88
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MYD88 | myeloid differentiation primary response 88 | NM_002468 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Constantly expressed in human cells and bat cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 61 | 59 | 39 | 49 | 71 | 62 | 56 | 78 | 55 |
Read_Max |  | R. aegyptiacus | Transcriptome | 115 | 90 | 117 | 98 | 82 | 104 | 77 | 128 | 102 |
Read_Max |  | R. aegyptiacus | Genome | 127 | 101 | 97 | 88 | 72 | 62 | 68 | 158 | 113 |
DESeq | | H. sapiens | Genome | 465.77 | 567.03 | 434.86 | 510.89 | 604.21 | 408.94 | 502.76 | 694.84 | 644.71 |
DESeq | | R. aegyptiacus | Transcriptome | 564.73 | 582.83 | 674.07 | 581.53 | 602.2 | 569.45 | 526.06 | 603.31 | 532.82 |
DESeq | | R. aegyptiacus | Genome | 973.69 | 990.26 | 1132.51 | 1102.03 | 1048.05 | 1074.35 | 1021.08 | 958.67 | 936.67 |