DUSP9

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
DUSP9 MKP-4, MKP4 dual specificity phosphatase 9 NM_001395 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. No complete homologous transcript could be found in the R.~aegyptiacus assembly.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome735 1062 886 1111 1549 1760 1495 1274 864
Read_Max
batR. aegyptiacusTranscriptome 2 4 3 5 1 2 4 2 4
Read_Max
bat_genomeR. aegyptiacusGenome 0 0 1 4 0 1 0 0 2
DESeq
humanH. sapiensGenome 9123.93 12976.84 9466.59 15071.71 12648.89 14641.95 14531.9 12018.43 9334.79
DESeq
batR. aegyptiacusTranscriptome 4.36 10.08 7.11 12.9 3.19 9.98 15.46 3.48 8.0
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.0 1.12 3.95 0.0 2.61 0.0 0.0 1.71

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 9123.93 15071.71 14531.9 0.72 0.67 -0.05
7h 12976.84 12648.89 12018.43 -0.04 -0.11 -0.07
23h 9466.59 14641.95 9334.79 0.63 -0.02 -0.65

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 9123.93 12976.84 9466.59 0.51 0.05 -0.46
Ebov 15071.71 12648.89 14641.95 -0.25 -0.04 0.21
Marv 14531.9 12018.43 9334.79 -0.27 -0.64 -0.36

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4.36 12.9 15.46 1.56 1.83 0.26
7h 10.08 3.19 3.48 -1.66 -1.53 0.13
23h 7.11 9.98 8.0 0.49 0.17 -0.32

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4.36 10.08 7.11 1.21 0.71 -0.5
Ebov 12.9 3.19 9.98 -2.02 -0.37 1.65
Marv 15.46 3.48 8.0 -2.15 -0.95 1.2