ITGB1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ITGB1 RP11-479G22.2, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB,CD29 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) NM_002211 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

This gene was found with very expression level in both human and bats samples. 0.5 times down-regulation was found in Human-Ebola-23h sample.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome1865 1968 2367 2072 3733 1815 2535 2796 2222
Read_Max
batR. aegyptiacusTranscriptome 8969 7817 6048 8755 6988 6711 6960 9795 8106
Read_Max
bat_genomeR. aegyptiacusGenome 9968 8747 4427 7493 5812 3322 5881 11563 7352
DESeq
humanH. sapiensGenome 25566.53 27835.37 29019.28 29529.86 31493.09 20692.56 28777.7 26762.45 27494.57
DESeq
batR. aegyptiacusTranscriptome 101384.95 95119.63 91401.26 112188.68 112460.17 88874.16 114862.49 113187.43 89794.23
DESeq
bat_genomeR. aegyptiacusGenome 108576.2 115143.41 88360.67 106641.31 118771.15 97786.95 126551.47 116659.8 94323.21

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 25566.53 29529.86 28777.7 0.21 0.17 -0.04
7h 27835.37 31493.09 26762.45 0.18 -0.06 -0.23
23h 29019.28 20692.56 27494.57 -0.49 -0.08 0.41

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 25566.53 27835.37 29019.28 0.12 0.18 0.06
Ebov 29529.86 31493.09 20692.56 0.09 -0.51 -0.61
Marv 28777.7 26762.45 27494.57 -0.1 -0.07 0.04

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 101384.95 112188.68 114862.49 0.15 0.18 0.03
7h 95119.63 112460.17 113187.43 0.24 0.25 0.01
23h 91401.26 88874.16 89794.23 -0.04 -0.03 0.01

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 101384.95 95119.63 91401.26 -0.09 -0.15 -0.06
Ebov 112188.68 112460.17 88874.16 0.0 -0.34 -0.34
Marv 114862.49 113187.43 89794.23 -0.02 -0.36 -0.33