TNFSF4

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TNFSF4 GP34, CD252, OX4OL, TXGP1, CD134L, OX-40L,OX-40L, gp34, CD252 tumor necrosis factor (ligand) superfamily, member 4 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus.

This gene is with low expression both in human cells and bat cells. But a slightly different expression level was found in human cells probes.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome55 64 86 51 83 28 59 84 27
Read_Max
batR. aegyptiacusTranscriptome 12 19 11 13 13 17 9 15 14
Read_Max
bat_genomeR. aegyptiacusGenome 42 31 32 25 30 27 18 54 36
DESeq
humanH. sapiensGenome 711.35 789.36 1277.77 614.69 890.37 318.14 576.45 715.62 393.53
DESeq
batR. aegyptiacusTranscriptome 34.61 40.94 51.08 37.63 44.8 67.73 32.15 44.79 50.86
DESeq
bat_genomeR. aegyptiacusGenome 608.45 685.43 840.18 556.94 599.36 1228.39 542.02 621.67 680.67

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 711.35 614.69 576.45 -0.21 -0.3 -0.09
7h 789.36 890.37 715.62 0.17 -0.14 -0.32
23h 1277.77 318.14 393.53 -2.01 -1.7 0.31

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 711.35 789.36 1277.77 0.15 0.84 0.69
Ebov 614.69 890.37 318.14 0.53 -0.95 -1.48
Marv 576.45 715.62 393.53 0.31 -0.55 -0.86

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 34.61 37.63 32.15 0.12 -0.11 -0.23
7h 40.94 44.8 44.79 0.13 0.13 -0.0
23h 51.08 67.73 50.86 0.41 -0.01 -0.41

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 34.61 40.94 51.08 0.24 0.56 0.32
Ebov 37.63 44.8 67.73 0.25 0.85 0.6
Marv 32.15 44.79 50.86 0.48 0.66 0.18