TPP2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| TPP2 | tripeptidyl peptidase II |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.
The gene TPP2 is expressed throughout all datasets of human cells and bat cells, although slightly upregulated at 7 h and downregulated at 23 h no significant differences in expression pattern could be found.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 197 | 281 | 380 | 167 | 440 | 317 | 254 | 387 | 264 |
Read_Max |  | R. aegyptiacus | Transcriptome | 558 | 404 | 331 | 429 | 367 | 476 | 395 | 554 | 426 |
Read_Max |  | R. aegyptiacus | Genome | 588 | 412 | 272 | 364 | 299 | 266 | 339 | 643 | 447 |
DESeq | | H. sapiens | Genome | 3166.12 | 3788.81 | 5112.06 | 2946.24 | 3962.51 | 4085.62 | 2898.41 | 3663.62 | 4461.3 |
DESeq | | R. aegyptiacus | Transcriptome | 6843.94 | 5806.58 | 5953.55 | 6789.76 | 6561.68 | 6659.43 | 7547.56 | 7108.05 | 6129.21 |
DESeq | | R. aegyptiacus | Genome | 7402.79 | 7108.9 | 5856.72 | 6566.77 | 6984.77 | 7059.66 | 8121.37 | 7217.39 | 6352.09 |