RAC2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RAC2 EN-7, Gx, HSPC022, p21-Rac2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome.

Expression values are not available in both organisms. %%%%%%%%%%%%%%%%%%%%%

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome1 2 2 2 2 3 0 2 2
Read_Max
batR. aegyptiacusTranscriptome 10 10 5 7 8 12 6 9 6
Read_Max
bat_genomeR. aegyptiacusGenome 13 5 5 11 7 9 8 10 12
DESeq
humanH. sapiensGenome 2.01 3.04 3.98 3.28 1.0 6.26 1.0 2.6 3.17
DESeq
batR. aegyptiacusTranscriptome 27.88 23.69 16.88 19.31 17.43 35.65 18.8 20.0 13.25
DESeq
bat_genomeR. aegyptiacusGenome 59.3 30.12 43.52 57.27 49.11 92.68 71.97 42.82 53.94

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2.01 3.28 1.0 0.71 -1.01 -1.71
7h 3.04 1.0 2.6 -1.6 -0.23 1.38
23h 3.98 6.26 3.17 0.65 -0.33 -0.98

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2.01 3.04 3.98 0.6 0.99 0.39
Ebov 3.28 1.0 6.26 -1.71 0.93 2.65
Marv 1.0 2.6 3.17 1.38 1.66 0.29

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 27.88 19.31 18.8 -0.53 -0.57 -0.04
7h 23.69 17.43 20.0 -0.44 -0.24 0.2
23h 16.88 35.65 13.25 1.08 -0.35 -1.43

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 27.88 23.69 16.88 -0.23 -0.72 -0.49
Ebov 19.31 17.43 35.65 -0.15 0.88 1.03
Marv 18.8 20.0 13.25 0.09 -0.5 -0.59