TNFRSF17

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TNFRSF17 BCM, BCMA, CD269, TNFRSF13A,BCM, CD269, TNFRSF13A tumor necrosis factor receptor superfamily, member 17 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

This gene was found with no expression in human and the expression level in bats is very low.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome0 0 1 1 1 2 1 1 0
Read_Max
batR. aegyptiacusTranscriptome 5 11 6 3 3 12 10 5 5
Read_Max
bat_genomeR. aegyptiacusGenome 1096 798 557 775 565 577 696 1276 1003
DESeq
humanH. sapiensGenome 1.0 1.0 2.99 3.28 1.81 2.32 1.0 1.8 1.0
DESeq
batR. aegyptiacusTranscriptome 7.72 17.34 15.66 8.33 11.95 18.96 24.36 10.09 10.62
DESeq
bat_genomeR. aegyptiacusGenome 9827.98 8783.68 7521.46 8978.2 9299.63 9889.79 10696.55 9168.83 8079.02

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 3.28 1.0 1.71 0.0 -1.71
7h 1.0 1.81 1.8 0.86 0.85 -0.01
23h 2.99 2.32 1.0 -0.37 -1.58 -1.21

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 2.99 0.0 1.58 1.58
Ebov 3.28 1.81 2.32 -0.86 -0.5 0.36
Marv 1.0 1.8 1.0 0.85 0.0 -0.85

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7.72 8.33 24.36 0.11 1.66 1.55
7h 17.34 11.95 10.09 -0.54 -0.78 -0.24
23h 15.66 18.96 10.62 0.28 -0.56 -0.84

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7.72 17.34 15.66 1.17 1.02 -0.15
Ebov 8.33 11.95 18.96 0.52 1.19 0.67
Marv 24.36 10.09 10.62 -1.27 -1.2 0.07