TRADD
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| TRADD | Hs.89862 | TNFRSF1A-associated via death domain |  |
NONE | NONE | NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Expression values are not available. %%%%%%%%%%%%%%%%%%%%%
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 6 | 6 | 8 | 7 | 9 | 11 | 7 | 11 | 10 |
Read_Max |  | R. aegyptiacus | Transcriptome | 7 | 4 | 3 | 6 | 7 | 6 | 5 | 7 | 14 |
Read_Max |  | R. aegyptiacus | Genome | 41 | 46 | 26 | 30 | 22 | 13 | 19 | 45 | 40 |
DESeq | | H. sapiens | Genome | 52.75 | 117.27 | 131.06 | 64.88 | 77.42 | 72.06 | 86.97 | 140.09 | 115.17 |
DESeq | | R. aegyptiacus | Transcriptome | 24.52 | 20.97 | 18.1 | 25.72 | 29.47 | 16.4 | 22.14 | 24.96 | 31.61 |
DESeq | | R. aegyptiacus | Genome | 404.77 | 434.44 | 405.03 | 394.01 | 313.63 | 227.14 | 309.25 | 396.47 | 396.42 |