RRAS

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
RRAS	MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Tight junction, Regulation of actin cytoskeleton, HTLV-I infection, Proteoglycans in cancer	related RAS viral (r-ras) oncogene homolog	NM_006270	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens related RAS viral (r-ras) oncogene homolog (RRAS), mRNA.

The gene is stably but very lowly expressed in human cells. The bat cells homolog shows higher expression which is increased upon Marburg virus infection. %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

\igvfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00922/snapshots//hg19.goi.00922_igv.eps % \caption\igv of gene RRAS. % <- say something about the figure here \endfigure }

\sashimifigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00922/snapshots//hg19.goi.00922_sashimi.eps % \caption\sashimi of gene RRAS. % <- say something about the figure here \endfigure }

\ucscfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00922/snapshots//hg19.goi.00922_ucsc.eps % \caption\ucsc of gene RRAS. % <- say something about the figure here \endfigure }

\setcounterfigure0 \enddocument

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	5	4	5	10	9	19	6	10	10
Read_Max	R. aegyptiacus	Transcriptome	74	88	82	68	60	81	42	64	114
Read_Max	R. aegyptiacus	Genome	86	88	75	102	55	52	42	83	147
DESeq	H. sapiens	Genome	23.33	14.26	18.87	21.53	25.39	69.43	26.44	30.58	37.97
DESeq	R. aegyptiacus	Transcriptome	201.79	244.26	307.61	204.28	197.02	251.22	147.84	167.07	280.91
DESeq	R. aegyptiacus	Genome	351.49	340.43	529.99	436.47	305.82	395.54	272.14	293.39	462.34

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	23.33	21.53	26.44	-0.12	0.18	0.3
7h	14.26	25.39	30.58	0.83	1.1	0.27
23h	18.87	69.43	37.97	1.88	1.01	-0.87

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	23.33	14.26	18.87	-0.71	-0.31	0.4
Ebov	21.53	25.39	69.43	0.24	1.69	1.45
Marv	26.44	30.58	37.97	0.21	0.52	0.31

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	201.79	204.28	147.84	0.02	-0.45	-0.47
7h	244.26	197.02	167.07	-0.31	-0.55	-0.24
23h	307.61	251.22	280.91	-0.29	-0.13	0.16

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	201.79	244.26	307.61	0.28	0.61	0.33
Ebov	204.28	197.02	251.22	-0.05	0.3	0.35
Marv	147.84	167.07	280.91	0.18	0.93	0.75

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material