TNFRSF21

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TNFRSF21 DR6, CD358, BM-018,DR6, CD358 tumor necrosis factor receptor superfamily, member 21 NM_014452 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors.

This gene was found to be well expressed in both human cells and bat cells probes, but without significantly different expression.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome342 335 215 331 399 346 477 619 423
Read_Max
batR. aegyptiacusTranscriptome 77 80 54 64 54 58 64 72 94
Read_Max
bat_genomeR. aegyptiacusGenome 94 69 48 80 61 36 61 130 116
DESeq
humanH. sapiensGenome 5175.4 4793.38 2881.18 5205.94 4329.15 4552.77 5780.9 6362.23 6426.13
DESeq
batR. aegyptiacusTranscriptome 778.13 713.54 639.86 632.81 682.15 616.93 788.58 609.92 817.98
DESeq
bat_genomeR. aegyptiacusGenome 1164.47 977.49 975.19 1113.88 1132.88 1011.69 1289.84 1017.35 1287.71

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 5175.4 5205.94 5780.9 0.01 0.16 0.15
7h 4793.38 4329.15 6362.23 -0.15 0.41 0.56
23h 2881.18 4552.77 6426.13 0.66 1.16 0.5

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 5175.4 4793.38 2881.18 -0.11 -0.85 -0.73
Ebov 5205.94 4329.15 4552.77 -0.27 -0.19 0.07
Marv 5780.9 6362.23 6426.13 0.14 0.15 0.01

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 778.13 632.81 788.58 -0.3 0.02 0.32
7h 713.54 682.15 609.92 -0.06 -0.23 -0.16
23h 639.86 616.93 817.98 -0.05 0.35 0.41

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 778.13 713.54 639.86 -0.13 -0.28 -0.16
Ebov 632.81 682.15 616.93 0.11 -0.04 -0.14
Marv 788.58 609.92 817.98 -0.37 0.05 0.42