MRAS

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MRAS MRAS, M-RAs, R-RAS3, RRAS3,M-RAs muscle RAS oncogene homolog pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

MRAS is expressed at much higher level in the bat cells cell lines compared to the human cells. No differential expression due to Ebola or Marburg infection.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome18 17 16 20 19 44 31 23 19
Read_Max
batR. aegyptiacusTranscriptome 268 231 215 209 225 351 207 235 281
Read_Max
bat_genomeR. aegyptiacusGenome 378 275 216 278 239 231 221 388 353
DESeq
humanH. sapiensGenome 312.54 260.05 221.41 404.8 306.67 890.56 411.53 340.72 352.21
DESeq
batR. aegyptiacusTranscriptome 1017.57 976.77 923.26 923.08 1007.39 1199.49 983.25 869.35 975.43
DESeq
bat_genomeR. aegyptiacusGenome 4371.72 3633.4 3313.86 4576.99 3996.88 4884.84 4477.89 3719.71 4055.78

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 312.54 404.8 411.53 0.37 0.4 0.02
7h 260.05 306.67 340.72 0.24 0.39 0.15
23h 221.41 890.56 352.21 2.01 0.67 -1.34

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 312.54 260.05 221.41 -0.27 -0.5 -0.23
Ebov 404.8 306.67 890.56 -0.4 1.14 1.54
Marv 411.53 340.72 352.21 -0.27 -0.22 0.05

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1017.57 923.08 983.25 -0.14 -0.05 0.09
7h 976.77 1007.39 869.35 0.04 -0.17 -0.21
23h 923.26 1199.49 975.43 0.38 0.08 -0.3

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1017.57 976.77 923.26 -0.06 -0.14 -0.08
Ebov 923.08 1007.39 1199.49 0.13 0.38 0.25
Marv 983.25 869.35 975.43 -0.18 -0.01 0.17