MRAS
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MRAS | MRAS, M-RAs, R-RAS3, RRAS3,M-RAs | muscle RAS oncogene homolog |  |
 |
 |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
MRAS is expressed at much higher level in the bat cells cell lines compared to the human cells. No differential expression due to Ebola or Marburg infection.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 18 | 17 | 16 | 20 | 19 | 44 | 31 | 23 | 19 |
Read_Max |  | R. aegyptiacus | Transcriptome | 268 | 231 | 215 | 209 | 225 | 351 | 207 | 235 | 281 |
Read_Max |  | R. aegyptiacus | Genome | 378 | 275 | 216 | 278 | 239 | 231 | 221 | 388 | 353 |
DESeq | | H. sapiens | Genome | 312.54 | 260.05 | 221.41 | 404.8 | 306.67 | 890.56 | 411.53 | 340.72 | 352.21 |
DESeq | | R. aegyptiacus | Transcriptome | 1017.57 | 976.77 | 923.26 | 923.08 | 1007.39 | 1199.49 | 983.25 | 869.35 | 975.43 |
DESeq | | R. aegyptiacus | Genome | 4371.72 | 3633.4 | 3313.86 | 4576.99 | 3996.88 | 4884.84 | 4477.89 | 3719.71 | 4055.78 |