VEGFB
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| VEGFB | VEGFL | vascular endothelial growth factor B | NM_003377 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
The gene VEGFB is weakly expressed in human cells datasets, no significant changes in expression patterns were visible.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 24 | 24 | 24 | 22 | 26 | 23 | 18 | 24 | 23 |
Read_Max |  | R. aegyptiacus | Transcriptome | 27 | 32 | 47 | 18 | 34 | 34 | 19 | 25 | 34 |
Read_Max |  | R. aegyptiacus | Genome | 79 | 55 | 85 | 52 | 45 | 52 | 44 | 106 | 149 |
DESeq | | H. sapiens | Genome | 136.98 | 124.4 | 159.85 | 108.22 | 116.44 | 128.64 | 88.72 | 144.08 | 166.28 |
DESeq | | R. aegyptiacus | Transcriptome | 88.37 | 96.31 | 158.58 | 53.19 | 101.75 | 116.49 | 85.54 | 71.23 | 106.84 |
DESeq | | R. aegyptiacus | Genome | 300.79 | 288.41 | 527.76 | 315.99 | 349.35 | 405.98 | 346.36 | 321.14 | 470.05 |