RIPK1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
RIPK1	Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1,RIP	receptor (TNFRSF)-interacting serine-threonine kinase 1	NM_003804	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

RIPK1 (receptor (TNFRSF)-interacting serine-threonine kinase 1) is a protein-coding gene. GO annotations related to this gene include protein kinase activity and identical protein binding. An important paralog of this gene is RIPK3.

The gene RIPK is expressed at low levels throughout all human cells datasets. Only two of the four annotated transcript isoforms are present.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	73	93	70	73	109	107	95	112	81
Read_Max	R. aegyptiacus	Transcriptome	78	66	53	66	49	81	58	70	71
Read_Max	R. aegyptiacus	Genome	87	72	47	66	47	47	51	82	82
DESeq	H. sapiens	Genome	1358.78	1347.23	1239.05	1467.92	1325.3	1245.86	1531.72	1251.18	1234.05
DESeq	R. aegyptiacus	Transcriptome	780.65	724.43	619.1	631.9	672.29	883.83	860.89	650.4	777.74
DESeq	R. aegyptiacus	Genome	1047.6	888.04	747.57	1009.21	939.78	1194.45	1156.02	869.86	981.2

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1358.78	1467.92	1531.72	0.11	0.17	0.06
7h	1347.23	1325.3	1251.18	-0.02	-0.11	-0.08
23h	1239.05	1245.86	1234.05	0.01	-0.01	-0.01

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1358.78	1347.23	1239.05	-0.01	-0.13	-0.12
Ebov	1467.92	1325.3	1245.86	-0.15	-0.24	-0.09
Marv	1531.72	1251.18	1234.05	-0.29	-0.31	-0.02

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	780.65	631.9	860.89	-0.3	0.14	0.45
7h	724.43	672.29	650.4	-0.11	-0.16	-0.05
23h	619.1	883.83	777.74	0.51	0.33	-0.18

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	780.65	724.43	619.1	-0.11	-0.33	-0.23
Ebov	631.9	672.29	883.83	0.09	0.48	0.39
Marv	860.89	650.4	777.74	-0.4	-0.15	0.26

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material