FGF1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FGF1 B2R5T0, D3DQF2, FGF1_HUMAN, FGFA, NM_001144892, NP_001244139, P05230, P07502, Q16588, uc003lmm.3,AFGF, ECGF, ECGFA, ECGFB, HBGF1, ECGF-beta, FGF-alpha, GLIO703 fibroblast growth factor 1 (acidic) NM_000800 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens fibroblast growth factor 1 (acidic) (FGF1), transcript variant 4 protein coding gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

Due to too few reads mapped on this locus, no (differential) expression can be confirmed. Furthermore no homolog sequence was found in bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4 2 3 3 3 5 3 2 4
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 0 0 2 2 0 1 0 3 0
DESeq
humanH. sapiensGenome 48.69 32.62 10.93 30.66 41.65 20.74 29.07 16.19 74.94
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.0 2.23 1.97 0.0 2.61 0.0 1.59 0.0

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 48.69 30.66 29.07 -0.67 -0.74 -0.08
7h 32.62 41.65 16.19 0.35 -1.01 -1.36
23h 10.93 20.74 74.94 0.92 2.78 1.85

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 48.69 32.62 10.93 -0.58 -2.16 -1.58
Ebov 30.66 41.65 20.74 0.44 -0.56 -1.01
Marv 29.07 16.19 74.94 -0.84 1.37 2.21

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA