RAC3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases.

Slight but clear expression in all human cells samples and no expression in the bat cells homolog. No significant differences between the various samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome18 25 16 32 34 26 39 39 25
Read_Max
batR. aegyptiacusTranscriptome 2 3 2 2 2 2 NA 3 2
Read_Max
bat_genomeR. aegyptiacusGenome 8 11 4 7 3 2 3 10 6
DESeq
humanH. sapiensGenome 78.12 116.25 71.49 125.33 79.04 97.06 120.3 133.69 141.27
DESeq
batR. aegyptiacusTranscriptome 2.68 4.63 5.89 5.58 3.19 3.57 1.0 5.13 2.75
DESeq
bat_genomeR. aegyptiacusGenome 17.19 27.38 20.08 23.7 17.86 7.83 13.49 27.75 19.69

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 78.12 125.33 120.3 0.68 0.62 -0.06
7h 116.25 79.04 133.69 -0.56 0.2 0.76
23h 71.49 97.06 141.27 0.44 0.98 0.54

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 78.12 116.25 71.49 0.57 -0.13 -0.7
Ebov 125.33 79.04 97.06 -0.67 -0.37 0.3
Marv 120.3 133.69 141.27 0.15 0.23 0.08

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2.68 5.58 1.0 1.06 -1.42 -2.48
7h 4.63 3.19 5.13 -0.54 0.15 0.69
23h 5.89 3.57 2.75 -0.72 -1.1 -0.38

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2.68 4.63 5.89 0.79 1.14 0.35
Ebov 5.58 3.19 3.57 -0.81 -0.64 0.16
Marv 1.0 5.13 2.75 2.36 1.46 -0.9