TNFRSF10B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TNFRSF10B DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9,,DR5, KILLER, TRICK2A, TRAIL-R2, TRICKB, CD262 tumor necrosis factor receptor superfamily, member 10b NM_147187 pdf NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

This gene was found to be with no significant different expression in human cells probes, and no promising homolog was found in bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome438 407 449 325 414 777 429 521 428
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA
DESeq
humanH. sapiensGenome 4139.3 3959.13 5478.41 4120.01 4500.68 8301.84 4149.3 4458.18 5905.29
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4139.3 4120.01 4149.3 -0.01 0.0 0.01
7h 3959.13 4500.68 4458.18 0.18 0.17 -0.01
23h 5478.41 8301.84 5905.29 0.6 0.11 -0.49

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4139.3 3959.13 5478.41 -0.06 0.4 0.47
Ebov 4120.01 4500.68 8301.84 0.13 1.01 0.88
Marv 4149.3 4458.18 5905.29 0.1 0.51 0.41

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA