MAP4K3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MAP4K3 GLK, MEKKK3, MEKKK 3, MAPKKKK3, RAB8IPL1 mitogen-activated protein kinase kinase kinase kinase 3 NM_003618 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

MAP4K3 is expressed in both human cells and bat cells and is very slightly down-regulated in Ebola-infected cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome128 152 156 116 179 136 165 149 151
Read_Max
batR. aegyptiacusTranscriptome 262 242 148 213 168 175 204 196 213
Read_Max
bat_genomeR. aegyptiacusGenome 362 313 168 296 204 119 227 349 257
DESeq
humanH. sapiensGenome 2024.48 2089.7 2422.5 2070.2 2301.65 1831.45 1931.73 1854.69 2099.58
DESeq
batR. aegyptiacusTranscriptome 2166.04 2131.35 1632.97 2063.09 2077.29 1755.11 2476.1 1964.07 1711.06
DESeq
bat_genomeR. aegyptiacusGenome 4583.13 4643.74 3784.72 4384.43 4635.3 3717.81 5082.88 4486.49 3579.74

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2024.48 2070.2 1931.73 0.03 -0.07 -0.1
7h 2089.7 2301.65 1854.69 0.14 -0.17 -0.31
23h 2422.5 1831.45 2099.58 -0.4 -0.21 0.2

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2024.48 2089.7 2422.5 0.05 0.26 0.21
Ebov 2070.2 2301.65 1831.45 0.15 -0.18 -0.33
Marv 1931.73 1854.69 2099.58 -0.06 0.12 0.18

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2166.04 2063.09 2476.1 -0.07 0.19 0.26
7h 2131.35 2077.29 1964.07 -0.04 -0.12 -0.08
23h 1632.97 1755.11 1711.06 0.1 0.07 -0.04

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2166.04 2131.35 1632.97 -0.02 -0.41 -0.38
Ebov 2063.09 2077.29 1755.11 0.01 -0.23 -0.24
Marv 2476.1 1964.07 1711.06 -0.33 -0.53 -0.2