ATM

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ATM AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1,TEL1 ATM serine/threonine kinase NM_000051 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The ATM serine/threonine kinase (EC:2.7.11.1) gene is involved in the NF-kappa B, FoxO and p53 signaling pathways, Cell cycle, Apoptosis, HTLV-I infection, transcriptional misregulation in cancer, MicroRNAs in cancer.

It did not present a particularly interesting differential expression pattern in the samples analyzed

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome86 86 121 72 149 128 75 80 107
Read_Max
batR. aegyptiacusTranscriptome 164 111 95 135 124 155 132 146 125
Read_Max
bat_genomeR. aegyptiacusGenome 180 153 84 109 108 99 121 189 146
DESeq
humanH. sapiensGenome 3820.66 3698.04 5325.52 3112.78 4299.88 4563.3 2950.16 3024.94 4947.34
DESeq
batR. aegyptiacusTranscriptome 5070.41 3658.99 3554.45 5555.44 5493.97 5118.33 4871.11 4946.68 3826.98
DESeq
bat_genomeR. aegyptiacusGenome 6295.89 6934.58 4149.58 4850.52 6828.51 6477.44 6201.79 5963.75 4771.56

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3820.66 3112.78 2950.16 -0.3 -0.37 -0.08
7h 3698.04 4299.88 3024.94 0.22 -0.29 -0.51
23h 5325.52 4563.3 4947.34 -0.22 -0.11 0.12

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3820.66 3698.04 5325.52 -0.05 0.48 0.53
Ebov 3112.78 4299.88 4563.3 0.47 0.55 0.09
Marv 2950.16 3024.94 4947.34 0.04 0.75 0.71

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 5070.41 5555.44 4871.11 0.13 -0.06 -0.19
7h 3658.99 5493.97 4946.68 0.59 0.44 -0.15
23h 3554.45 5118.33 3826.98 0.53 0.11 -0.42

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 5070.41 3658.99 3554.45 -0.47 -0.51 -0.04
Ebov 5555.44 5493.97 5118.33 -0.02 -0.12 -0.1
Marv 4871.11 4946.68 3826.98 0.02 -0.35 -0.37