KITLG
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| KITLG | SCF, SF, Kitl, KL-1, FPH2 | KIT ligand | NM_003994 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.
The gene KITLG is expressed throughout human cells and bat cells datasets. Interestingly expression patterns in human cells and bat cells are directly inverted, while in human cells expression during infection goes down, it goes down in bat cells wild type while it remains stable in bat cells infection datasets.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 117 | 112 | 105 | 109 | 144 | 60 | 114 | 124 | 77 |
Read_Max |  | R. aegyptiacus | Transcriptome | 247 | 174 | 116 | 256 | 191 | 187 | 170 | 218 | 187 |
Read_Max |  | R. aegyptiacus | Genome | 289 | 257 | 98 | 212 | 168 | 153 | 171 | 353 | 264 |
DESeq | | H. sapiens | Genome | 1904.74 | 1967.31 | 1823.83 | 1766.78 | 1781.36 | 876.09 | 1699.27 | 1598.9 | 1679.86 |
DESeq | | R. aegyptiacus | Transcriptome | 1135.19 | 965.87 | 797.44 | 1239.9 | 1419.14 | 1255.95 | 1144.55 | 1241.14 | 1021.79 |
DESeq | | R. aegyptiacus | Genome | 3877.57 | 4207.48 | 2386.65 | 3580.62 | 4664.32 | 4356.15 | 4351.94 | 4338.21 | 3685.05 |