TNFSF13B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TNFSF13B DTL, BAFF, BLYS, CD257,BAFF, THANK, BLYS, TALL-1, TALL1, CD257 tumor necrosis factor (ligand) superfamily, member 13b pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.

This gene showed low expression in human cells, but a 3 times up-regulation was found in 23 h Eobla probe. And no homolog was found in bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4 3 4 6 4 3 3 4 3
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 0 0 0 0 2 0 0 0 0
DESeq
humanH. sapiensGenome 31.44 16.3 21.85 19.25 32.71 36.53 21.18 18.59 20.57
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.0 0.0 0.0 2.23 0.0 0.0 0.0 0.0

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 31.44 19.25 21.18 -0.71 -0.57 0.14
7h 16.3 32.71 18.59 1.0 0.19 -0.82
23h 21.85 36.53 20.57 0.74 -0.09 -0.83

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 31.44 16.3 21.85 -0.95 -0.52 0.42
Ebov 19.25 32.71 36.53 0.76 0.92 0.16
Marv 21.18 18.59 20.57 -0.19 -0.04 0.15

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA