AKT1S1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
AKT1S1	PRAS40, MGC2865, Lobe	AKT1 substrate 1 (proline-rich)	NM_032375	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein.

The gene is lowly expressed in human cells and downregulated after 7 h for all samples. The homolog in bat cells shows no expression.

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source		Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max		H. sapiens	Genome	126	87	60	97	91	146	134	144	79
Read_Max		R. aegyptiacus	Transcriptome	6	7	5	8	5	9	5	4	13
Read_Max		R. aegyptiacus	Genome	134	96	96	130	88	67	95	136	153
DESeq		H. sapiens	Genome	1075.66	1050.45	761.5	890.73	800.13	1909.09	1087.86	1051.35	939.38
DESeq		R. aegyptiacus	Transcriptome	17.8	15.52	20.54	25.72	26.19	18.96	15.46	5.96	25.49
DESeq		R. aegyptiacus	Genome	993.45	1002.13	1332.24	1196.83	990.01	1091.32	937.86	1057.0	1269.73

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1075.66	890.73	1087.86	-0.27	0.02	0.29
7h	1050.45	800.13	1051.35	-0.39	0.0	0.39
23h	761.5	1909.09	939.38	1.33	0.3	-1.02

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1075.66	1050.45	761.5	-0.03	-0.5	-0.46
Ebov	890.73	800.13	1909.09	-0.15	1.1	1.25
Marv	1087.86	1051.35	939.38	-0.05	-0.21	-0.16

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	17.8	25.72	15.46	0.53	-0.2	-0.73
7h	15.52	26.19	5.96	0.75	-1.38	-2.14
23h	20.54	18.96	25.49	-0.12	0.31	0.43

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	17.8	15.52	20.54	-0.2	0.21	0.4
Ebov	25.72	26.19	18.96	0.03	-0.44	-0.47
Marv	15.46	5.96	25.49	-1.38	0.72	2.1