STK11
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| STK11 | LKB1,PJS, LKB1 | serine/threonine kinase 11 | NM_000455 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
The gene is lowly expressed in all conditions.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 176 | 203 | 157 | 163 | 224 | 486 | 185 | 199 | 143 |
Read_Max |  | R. aegyptiacus | Transcriptome | 98 | 110 | 111 | 115 | 120 | 222 | 121 | 175 | 192 |
Read_Max |  | R. aegyptiacus | Genome | 114 | 134 | 96 | 108 | 106 | 135 | 103 | 219 | 208 |
DESeq | | H. sapiens | Genome | 2268.03 | 2459.91 | 1896.3 | 2058.79 | 2136.62 | 5137.04 | 2083.48 | 2302.33 | 2089.79 |
DESeq | | R. aegyptiacus | Transcriptome | 685.71 | 712.63 | 744.92 | 686.84 | 918.69 | 1134.05 | 810.83 | 825.56 | 861.71 |
DESeq | | R. aegyptiacus | Genome | 1516.82 | 1567.08 | 1254.13 | 1577.01 | 1811.49 | 2089.96 | 1624.95 | 1655.67 | 1567.69 |