TMEM67

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
TMEM67	MGC26979, JBTS6, NPHP11	transmembrane protein 67	NM_153704	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene.

The gene is not expressed in human cells and slightly in bat cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	11	10	6	6	8	10	7	14	12
Read_Max	R. aegyptiacus	Transcriptome	103	73	71	79	65	119	66	104	88
Read_Max	R. aegyptiacus	Genome	166	138	98	102	73	100	84	201	126
DESeq	H. sapiens	Genome	91.32	53.01	75.46	75.14	73.35	72.06	54.51	88.13	94.51
DESeq	R. aegyptiacus	Transcriptome	1118.39	1057.55	1326.37	1116.28	1030.38	1554.93	1118.97	1258.49	1118.0
DESeq	R. aegyptiacus	Genome	2283.4	2628.53	2783.87	2118.15	2194.32	3029.86	2292.92	2819.72	2196.13

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	91.32	75.14	54.51	-0.28	-0.74	-0.46
7h	53.01	73.35	88.13	0.47	0.73	0.26
23h	75.46	72.06	94.51	-0.07	0.32	0.39

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	91.32	53.01	75.46	-0.78	-0.28	0.51
Ebov	75.14	73.35	72.06	-0.03	-0.06	-0.03
Marv	54.51	88.13	94.51	0.69	0.79	0.1

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1118.39	1116.28	1118.97	-0.0	0.0	0.0
7h	1057.55	1030.38	1258.49	-0.04	0.25	0.29
23h	1326.37	1554.93	1118.0	0.23	-0.25	-0.48

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1118.39	1057.55	1326.37	-0.08	0.25	0.33
Ebov	1116.28	1030.38	1554.93	-0.12	0.48	0.59
Marv	1118.97	1258.49	1118.0	0.17	-0.0	-0.17

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material