HGS

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
HGS	AK294190, B4DFP5, B4DFP5_HUMAN,Hrs, ZFYVE8, Vps27	hepatocyte growth factor-regulated tyrosine kinase substrate	NM_004712	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

The gene is not differential expressed.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	88	127	118	96	195	302	141	204	128
Read_Max	R. aegyptiacus	Transcriptome	132	100	161	118	89	130	73	132	204
Read_Max	R. aegyptiacus	Genome	144	122	142	98	78	78	67	165	216
DESeq	H. sapiens	Genome	1451.13	2085.62	1703.69	1889.97	1805.75	3815.86	1986.99	2371.07	1769.03
DESeq	R. aegyptiacus	Transcriptome	983.12	1031.23	1510.82	1000.91	948.25	1245.69	848.65	1023.85	1340.18
DESeq	R. aegyptiacus	Genome	1246.97	1368.11	1784.13	1363.71	1175.29	1498.61	1085.17	1298.05	1628.48

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1451.13	1889.97	1986.99	0.38	0.45	0.07
7h	2085.62	1805.75	2371.07	-0.21	0.19	0.39
23h	1703.69	3815.86	1769.03	1.16	0.05	-1.11

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1451.13	2085.62	1703.69	0.52	0.23	-0.29
Ebov	1889.97	1805.75	3815.86	-0.07	1.01	1.08
Marv	1986.99	2371.07	1769.03	0.25	-0.17	-0.42

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	983.12	1000.91	848.65	0.03	-0.21	-0.24
7h	1031.23	948.25	1023.85	-0.12	-0.01	0.11
23h	1510.82	1245.69	1340.18	-0.28	-0.17	0.11

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	983.12	1031.23	1510.82	0.07	0.62	0.55
Ebov	1000.91	948.25	1245.69	-0.08	0.32	0.39
Marv	848.65	1023.85	1340.18	0.27	0.66	0.39

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material

HGS