HGS

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
HGS AK294190, B4DFP5, B4DFP5_HUMAN,Hrs, ZFYVE8, Vps27 hepatocyte growth factor-regulated tyrosine kinase substrate NM_004712 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

The gene is not differential expressed.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome88 127 118 96 195 302 141 204 128
Read_Max
batR. aegyptiacusTranscriptome 132 100 161 118 89 130 73 132 204
Read_Max
bat_genomeR. aegyptiacusGenome 144 122 142 98 78 78 67 165 216
DESeq
humanH. sapiensGenome 1451.13 2085.62 1703.69 1889.97 1805.75 3815.86 1986.99 2371.07 1769.03
DESeq
batR. aegyptiacusTranscriptome 983.12 1031.23 1510.82 1000.91 948.25 1245.69 848.65 1023.85 1340.18
DESeq
bat_genomeR. aegyptiacusGenome 1246.97 1368.11 1784.13 1363.71 1175.29 1498.61 1085.17 1298.05 1628.48

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1451.13 1889.97 1986.99 0.38 0.45 0.07
7h 2085.62 1805.75 2371.07 -0.21 0.19 0.39
23h 1703.69 3815.86 1769.03 1.16 0.05 -1.11

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1451.13 2085.62 1703.69 0.52 0.23 -0.29
Ebov 1889.97 1805.75 3815.86 -0.07 1.01 1.08
Marv 1986.99 2371.07 1769.03 0.25 -0.17 -0.42

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 983.12 1000.91 848.65 0.03 -0.21 -0.24
7h 1031.23 948.25 1023.85 -0.12 -0.01 0.11
23h 1510.82 1245.69 1340.18 -0.28 -0.17 0.11

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 983.12 1031.23 1510.82 0.07 0.62 0.55
Ebov 1000.91 948.25 1245.69 -0.08 0.32 0.39
Marv 848.65 1023.85 1340.18 0.27 0.66 0.39