LPIN2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
LPIN2 KIAA0249 lipin 2 NM_014646 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance.

It is upregulated in human cells after Ebola infection and a putative novel intronic ncRNA could be identified. In bat cells it is constantly expressed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome241 341 365 250 448 708 308 454 264
Read_Max
batR. aegyptiacusTranscriptome 177 150 122 165 130 148 116 186 145
Read_Max
bat_genomeR. aegyptiacusGenome 200 161 103 137 113 85 100 214 147
DESeq
humanH. sapiensGenome 7196.85 9867.25 10008.67 7462.21 8937.77 10960.0 7315.13 8966.51 7863.61
DESeq
batR. aegyptiacusTranscriptome 2703.73 2544.35 2270.62 2625.31 2549.27 2409.53 2503.91 2571.33 2013.7
DESeq
bat_genomeR. aegyptiacusGenome 3733.19 3501.97 2956.81 3641.84 3686.59 3384.93 3704.21 3458.04 2886.22

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7196.85 7462.21 7315.13 0.05 0.02 -0.03
7h 9867.25 8937.77 8966.51 -0.14 -0.14 0.0
23h 10008.67 10960.0 7863.61 0.13 -0.35 -0.48

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7196.85 9867.25 10008.67 0.46 0.48 0.02
Ebov 7462.21 8937.77 10960.0 0.26 0.55 0.29
Marv 7315.13 8966.51 7863.61 0.29 0.1 -0.19

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2703.73 2625.31 2503.91 -0.04 -0.11 -0.07
7h 2544.35 2549.27 2571.33 0.0 0.02 0.01
23h 2270.62 2409.53 2013.7 0.09 -0.17 -0.26

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2703.73 2544.35 2270.62 -0.09 -0.25 -0.16
Ebov 2625.31 2549.27 2409.53 -0.04 -0.12 -0.08
Marv 2503.91 2571.33 2013.7 0.04 -0.31 -0.35