EHD1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
EHD1 H-PAST, HPAST1, FLJ42622, FLJ44618 EH-domain containing 1 NM_006795 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene.

The gene is moderately and equally expressed in human cells and in the bat cells homolog.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome84 105 62 92 117 81 97 129 77
Read_Max
batR. aegyptiacusTranscriptome 201 172 112 134 125 134 126 156 172
Read_Max
bat_genomeR. aegyptiacusGenome 220 140 98 169 111 81 111 184 187
DESeq
humanH. sapiensGenome 1203.52 1252.38 825.04 1127.99 1029.38 1032.68 1046.63 1283.16 989.4
DESeq
batR. aegyptiacusTranscriptome 1584.66 1568.58 1262.85 1351.61 1276.78 1341.92 1276.93 1308.06 1393.54
DESeq
bat_genomeR. aegyptiacusGenome 1426.59 1262.24 1104.62 1507.89 1282.44 1301.49 1250.48 1139.46 1260.31

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1203.52 1127.99 1046.63 -0.09 -0.2 -0.11
7h 1252.38 1029.38 1283.16 -0.28 0.04 0.32
23h 825.04 1032.68 989.4 0.32 0.26 -0.06

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1203.52 1252.38 825.04 0.06 -0.54 -0.6
Ebov 1127.99 1029.38 1032.68 -0.13 -0.13 0.0
Marv 1046.63 1283.16 989.4 0.29 -0.08 -0.38

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1584.66 1351.61 1276.93 -0.23 -0.31 -0.08
7h 1568.58 1276.78 1308.06 -0.3 -0.26 0.03
23h 1262.85 1341.92 1393.54 0.09 0.14 0.05

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1584.66 1568.58 1262.85 -0.01 -0.33 -0.31
Ebov 1351.61 1276.78 1341.92 -0.08 -0.01 0.07
Marv 1276.93 1308.06 1393.54 0.03 0.13 0.09