ARFGAP1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ARFGAP1 | ARF1GAP, bA261N11.3, FLJ10767,FLJ10767 | ADP-ribosylation factor GTPase activating protein 1 | NM_018209 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.
It is constantly expressed in both human cells and bat cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 94 | 163 | 168 | 161 | 263 | 364 | 201 | 244 | 190 |
Read_Max |  | R. aegyptiacus | Transcriptome | 107 | 149 | 104 | 95 | 75 | 112 | 99 | 131 | 162 |
Read_Max |  | R. aegyptiacus | Genome | 114 | 98 | 84 | 144 | 65 | 61 | 86 | 145 | 173 |
DESeq | | H. sapiens | Genome | 1986.94 | 2947.41 | 3035.07 | 2536.74 | 2850.39 | 4396.18 | 2684.37 | 3407.83 | 2914.0 |
DESeq | | R. aegyptiacus | Transcriptome | 614.3 | 710.81 | 697.28 | 523.85 | 534.31 | 652.86 | 699.59 | 519.86 | 821.48 |
DESeq | | R. aegyptiacus | Genome | 822.44 | 697.29 | 883.7 | 951.93 | 696.47 | 818.49 | 862.52 | 684.31 | 1012.02 |