USP8
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| USP8 | HumORF8, KIAA0055, UBPY, SPG59 | ubiquitin specific peptidase 8 | NM_005154 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.
It is expressed constantly in human cells and bat cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 134 | 152 | 199 | 125 | 241 | 263 | 149 | 195 | 190 |
Read_Max |  | R. aegyptiacus | Transcriptome | 411 | 303 | 301 | 398 | 372 | 440 | 324 | 470 | 448 |
Read_Max |  | R. aegyptiacus | Genome | 450 | 423 | 252 | 306 | 307 | 250 | 284 | 569 | 487 |
DESeq | | H. sapiens | Genome | 2041.74 | 2065.22 | 2536.67 | 2129.51 | 2491.88 | 3298.7 | 1962.43 | 2013.76 | 2692.18 |
DESeq | | R. aegyptiacus | Transcriptome | 4098.36 | 3598.17 | 3572.77 | 4556.45 | 4443.78 | 4345.85 | 5042.42 | 4522.84 | 3694.02 |
DESeq | | R. aegyptiacus | Genome | 4549.61 | 5078.18 | 3696.57 | 4293.58 | 5036.0 | 4867.87 | 5717.12 | 4879.0 | 4049.79 |