NCK1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| NCK1 | NCK Adaptor Protein 1, Melanoma NCK Protein, NCKalpha,NCKalpha | NCK adaptor protein 1 | NM_006153 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Expression in all samples, in human cells after Marburg infection it is downregulated at both timepoints.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 69 | 85 | 95 | 56 | 115 | 117 | 112 | 98 | 88 |
Read_Max |  | R. aegyptiacus | Transcriptome | 117 | 97 | 75 | 114 | 119 | 117 | 117 | 138 | 117 |
Read_Max |  | R. aegyptiacus | Genome | 141 | 117 | 65 | 96 | 74 | 70 | 102 | 164 | 131 |
DESeq | | H. sapiens | Genome | 677.86 | 688.39 | 771.43 | 650.05 | 735.09 | 735.28 | 754.52 | 661.26 | 779.54 |
DESeq | | R. aegyptiacus | Transcriptome | 719.32 | 572.84 | 702.16 | 760.09 | 746.76 | 695.2 | 736.3 | 747.89 | 718.26 |
DESeq | | R. aegyptiacus | Genome | 935.88 | 856.1 | 868.08 | 740.61 | 798.04 | 853.74 | 909.75 | 844.49 | 822.8 |