AP2S1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
AP2S1 AP17, CLAPS2, FBH3, FBHOk, HHC3,FBHOk adaptor-related protein complex 2, sigma 1 subunit pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The adaptor-related protein complex 2, sigma 1 subunit is involved in Endocytosis, Synaptic vesicle cycle, Endocrine and other factor-regulated calcium reabsorption and Huntington's disease.

It did not presented a particular pattern of differential expression in the samples analyzed. It only seems to be slightly upregulated after 23 h of Marburg virus infection in bat cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome73 119 82 90 144 114 108 115 93
Read_Max
batR. aegyptiacusTranscriptome 92 88 75 102 94 96 71 97 143
Read_Max
bat_genomeR. aegyptiacusGenome 86 95 61 75 74 59 60 105 138
DESeq
humanH. sapiensGenome 320.66 396.71 310.76 394.54 334.31 323.4 345.74 354.31 370.7
DESeq
batR. aegyptiacusTranscriptome 187.51 241.54 273.4 286.69 261.63 325.64 234.61 224.08 323.77
DESeq
bat_genomeR. aegyptiacusGenome 246.64 313.05 324.69 303.16 308.05 374.65 294.63 255.33 357.03

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 320.66 394.54 345.74 0.3 0.11 -0.19
7h 396.71 334.31 354.31 -0.25 -0.16 0.08
23h 310.76 323.4 370.7 0.06 0.25 0.2

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 320.66 396.71 310.76 0.31 -0.05 -0.35
Ebov 394.54 334.31 323.4 -0.24 -0.29 -0.05
Marv 345.74 354.31 370.7 0.04 0.1 0.07

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 187.51 286.69 234.61 0.61 0.32 -0.29
7h 241.54 261.63 224.08 0.12 -0.11 -0.22
23h 273.4 325.64 323.77 0.25 0.24 -0.01

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 187.51 241.54 273.4 0.37 0.54 0.18
Ebov 286.69 261.63 325.64 -0.13 0.18 0.32
Marv 234.61 224.08 323.77 -0.07 0.46 0.53